fosphenytoin will minimize the extent or impact of diazepam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.apalutamide will reduce the extent or outcome of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a powerful CYP2C19 inducer, with m